GENERAL CATALOGUE
Artepillin C
HY-N10319 · 1 mg
MedChemExpress · Cat: HY-N10319
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Catalog No: HY-N10319
CAS No: 72944-19-5
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist EC50=1.8 ?M . Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce necroptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation.
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