GENERAL CATALOGUE
AS-99
HY-141429C · 50 mg
MedChemExpress · Cat: HY-141429C
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Manufacturer product page
medchemexpress.com/as-99-1.htmlCatalog No: HY-141429C
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
AS-99 is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor IC50= 0.79 ?M, Kd= 0.89 ?M with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo.
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