GENERAL CATALOGUE
AS1269574
HY-107535 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-107535
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medchemexpress.com/as1269574.htmlCatalog No: HY-107535
CAS No: 330981-72-1
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 ?M in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 GLP-1 secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic ?-cells only under high-glucose conditions. AS1269574 has the potential for the research of type 2 diabetes.