GENERAL CATALOGUE
Aspulvinone O
HY-N6237 · 1 mg
MedChemExpress · Cat: HY-N6237
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Catalog No: HY-N6237
CAS No: 914071-54-8
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Aspulvinone O is a selective inhibitor of glutamate oxaloacetate aminotransferase GOT1. Aspulvinone O inhibits glutamine metabolism and reduces NADPH production, thereby inducing oxidative stress and apoptosis in pancreatic ductal adenocarcinoma PDAC cells. Aspulvinone O inhibits PDAC cell proliferation in vitro and tumor growth in xenograft models.
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