

HY-P99444 · 1 mg
MedChemExpress · Cat: HY-P99444
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medchemexpress.com/astegolimab.html
Description
Astegolimab MSTT 1041A; RG 6149 is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1?, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap NET formation. Astegolimab is used in chronic obstructive pulmonary disease COPD and myocardial research.







