

HY-163168 · 1 mg
MedChemExpress · Cat: HY-163168
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medchemexpress.com/atag-4531.htmlDescription
aTAG 4531 CFT-4531 is a potent, selective, and onmechanism tool degrader of MTH1 with DC50 value of 0.28 nM and Ki value of 1.8 nM. The degradation activity is due to the intricate formation of the ternary complex between the MTH1 aTAG, CRBN E3 ligase, and aTAG tool degrader. Red: MTH1 aTAG inhibitor HY-134725 , Blue: CRBN ligand HY-126457 , Black: linker HY-108374 .





