ATF2 Mouse Monoclonal Antibody

Description

EnkiLife offers the ATF2 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: HB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000 Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain. Research Area: TGF-beta signaling pathway,PI3K-Akt signaling pathway,MAPK signaling pathway