GENERAL CATALOGUE
ATI-2341
HY-P0172 · 1 mg
MedChemExpress · Cat: HY-P0172
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medchemexpress.com/ati-2341.htmlCatalog No: HY-P0172
CAS No: 1337878-62-2
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 CXCR4 , which functions as a biased ligand, favoring G?i activation over G?13. ATI-2341 activates the inhibitory heterotrimeric G protein Gi to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils PMNs and hematopoietic stem and progenitor cells HSPCs .
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