GENERAL CATALOGUE
ATR-IN-20
HY-151915 · 50 mg
MedChemExpress · Cat: HY-151915
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Manufacturer product page
medchemexpress.com/atr-in-20.htmlCatalog No: HY-151915
CAS No: 3012609-63-8
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
ATR-IN-20 is a potent ATR ATM/ATR inhibitor with an IC50 of 3 nM. ATR-IN-20 possess an inhibitory effect on mTOR IC50 of 18 nM while displaying good selectivity against PI3K? 100 nM , ATM 100 nM , and DNA-PK 662 nM . ATR-IN-20 exhibits excellent pharmacokinetic profile F = 30 % , and has anticancer effects.
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