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ATX inhibitor 12
GENERAL CATALOGUE

ATX inhibitor 12

HY-144743 · 50 mg

MedChemExpress · Cat: HY-144743

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Catalog No: HY-144743
CAS No: 2771312-16-2
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

ATX inhibitor 12 compound 20 is an orally active and potent ATX autotaxin inhibitor, with an IC50 of 1.72 nM. ATX inhibitor 12 effectively alleviates lung structural damage with fewer fibrotic lesions at an oral dose of 60 mg/kg in C57Bl/6J mice. ATX inhibitor 12 can be uesd for idiopathic pulmonary fibrosis IPF research.

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