

HY-163410 · 5 mg
MedChemExpress · Cat: HY-163410
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medchemexpress.com/au-24118.htmlDescription
AU-24118 is a selective and orally bioavailable PROTAC degrader of mSWI-SNF ATPases SMARCA2 and SMARCA4 and PBRM1. AU-24118 integrates a bait moiety binding to the bromodomains of SMARCA2 and SMARCA4, along with a ligand moiety for CRBN ligase. AU-24118 demonstrates tumor regression in prostate cancer model. AU-24118 can be studied to combat prostate cancer. Pink: PBRM1/SMARCA2,4 ligand HY-171774 ; Blue: CRBN ligand HY-171775 .

