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Aurora kinase inhibitor-3
GENERAL CATALOGUE

Aurora kinase inhibitor-3

HY-112373 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-112373

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Catalog No: HY-112373
CAS No: 879127-16-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Aurora kinase inhibitor-3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 ?M. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket.

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