GENERAL CATALOGUE
AV123
HY-151369 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-151369
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Catalog No: HY-151369
CAS No: 233605-81-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AV123 compound 12 is a non-cytotoxic RIPK1 inhibitor IC50=12.12 AAasAasAAmuM . AV123 blocks the TNF-?-induced necroptotic EC50=1.7 ?M but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases.
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