GENERAL CATALOGUE
Avacincaptad pegol sodium
HY-147080 · 1 mg
MedChemExpress · Cat: HY-147080
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medchemexpress.com/avacincaptad-pegol-sodium.htmlCatalog No: HY-147080
CAS No: 1491144-00-3
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Avacincaptad pegol ARC1905 sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 C5 , inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex MAC , and is used to study age-related macular degeneration AMD . Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy GA mice.
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