GENERAL CATALOGUE
Avapritinib (Standard)
HY-101561R · 5 mg
MedChemExpress · Cat: HY-101561R
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Manufacturer product page
medchemexpress.com/avapritinib-standard.htmlCatalog No: HY-101561R
CAS No: 1703793-34-3
Pack Size: 5 mg
Brand: MedChemExpress
Description
Avapritinib Standard is the analytical standard of Avapritinib. This product is intended for research and analytical applications. Avapritinib BLU-285 is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC50s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib BLU-285 binds the active conformation of the kinase and shows antitumor activity. Avapritinib BLU-285 attenuates the transport function of both ABCB1 and ABCG2.
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