GENERAL CATALOGUE
Avatrombopag hydrochloride
HY-13463B · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13463B
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medchemexpress.com/avatrombopag-hydrochloride.htmlCatalog No: HY-13463B
CAS No: 570403-17-7
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Avatrombopag AKR-501 hydrochloride is an orally active, nonpeptide thrombopoietin TPO receptor agonist EC50=3.3 nM . Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 CYP 2C9 and CYP3A.
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