

HY-168427 · 50 mg
MedChemExpress · Cat: HY-168427
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medchemexpress.com/avitinib-maleate-dihydrate.htmlDescription
Avitinib Abivertinib maleate dihydrate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib maleate dihydrate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate dihydrate shows anticancer effects.







