GENERAL CATALOGUE
AVP-13358
HY-165484 · 1 mg
MedChemExpress · Cat: HY-165484
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medchemexpress.com/avp-13358.htmlCatalog No: HY-165484
CAS No: 459805-03-9
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
AVP-13358 is an orally active IgE inhibitor that effectively suppresses immunoglobulin E IgE -mediated immune responses, with IC50 values of 8 and 3 nM for IgE inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell IgE receptor CD23 in human monocytes and the CD23 and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses.
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