GENERAL CATALOGUE
AX-024
HY-107390 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-107390
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medchemexpress.com/AX-024.html
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Catalog No: HY-107390
CAS No: 1370544-73-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-?, IFN-?, IL-10 and IL-17A.
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