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AX-024 hydrochloride
GENERAL CATALOGUE

AX-024 hydrochloride

HY-107390A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-107390A

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Catalog No: HY-107390A
CAS No: 1704801-24-0
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-?, IFN-?, IL-10 and IL-17A.

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