GENERAL CATALOGUE
AZ084
HY-119217 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-119217
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Catalog No: HY-119217
CAS No: 929300-19-6
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AZ084 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche PMN and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer.
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