GENERAL CATALOGUE
AZ1495
HY-111101 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-111101
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Catalog No: HY-111101
CAS No: 2196204-23-4
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 IRAK4 inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 ?M and 0.023 ?M, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 ?M. AZ1495 can be used for the research of diffuse large B-cell lymphoma DLBCL .
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