GENERAL CATALOGUE
AZ1729
HY-121140 · 5 mg
MedChemExpress · Cat: HY-121140
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Catalog No: HY-121140
CAS No: 2016864-46-1
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
AZ1729 is a potent free fatty acid 2 receptor FFA2 activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in Gi-mediated pathways, but not at those transduced by Gq/G11. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2.
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