GENERAL CATALOGUE
AZD-5672
HY-119101 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-119101
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medchemexpress.com/azd-5672.htmlCatalog No: HY-119101
CAS No: 780750-65-4
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AZD-5672 is an orally active, potent, and selective CCR5 antagonist IC50=0.32 nM . AZD-5672 shows moderate activity against the hERG ion channel binding IC50=7.3 ?M . AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport IC50=32 ?M . AZD-5672 can be used for the research of rheumatoid arthritis.