GENERAL CATALOGUE
AZD4144
HY-162877 · 5 mg
MedChemExpress · Cat: HY-162877
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medchemexpress.com/azd4144.htmlCatalog No: HY-162877
CAS No: 2890191-41-8
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
AZD4144 is an orally active NLRP3 inhibitor EC50: 0.082 ?M . AZD4144 effectively inhibits the release of IL-1? when NLRP3 is overactivated, exerting an anti-inflammatory effect. AZD4144 has low inhibitory effect on hERG and low cardiotoxicity. AZD4144 has the potential to study diseases and conditions associated with NLRP3 inflammasome activation.
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