GENERAL CATALOGUE
AZD4877
HY-13224 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13224
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Catalog No: HY-13224
CAS No: 758722-49-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AZD4877 is another isostere to Ispinesib HY-50759 and also a kinesin spindle protein Eg5 inhibitor with IC50 of 2 nM.AZD4877 arrests cell mitosis, leads to the formation of the monopolar spindle phenotype and induces apoptosis. AZD4877 inhibits circulating peripheral blood mononuclear cells PBMCs and has anti-cancer activity.
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