Azido-PEG5-acid

Description

Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO CPT: Camptothecin HY-16560 . Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates ADCs . Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction CuAAc with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition SPAAC reactions with molecules containing DBCO or BCN groups.