GENERAL CATALOGUE
AZM475271
HY-13561 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-13561
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Catalog No: HY-13561
CAS No: 476159-98-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
AZM475271 M475271 is an orally active and selective Src kinase inhibitor. AZM475271 inhibits phosphorylation of c-Src kinase, Lck, c-yes IC50s = 0.01, 0.03, 0.08 ?M, respectively . AZM475271 induces apoptosis. AZM475271 reduces tumor cell proliferation and migration in vitro and in vivo, and reduces microvessel density MVD . AZM475271 inhibits tumor growth and metastasis. AZM475271 sensitizes tumor cells to the cytotoxic effects of Gemcitabine HY-17026 .
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