GENERAL CATALOGUE
B-355252
HY-120553 · 5 mg
MedChemExpress · Cat: HY-120553
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Catalog No: HY-120553
CAS No: 1261576-81-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line HT22 model of Parkinson disease PD .
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