B7H3 Mouse Monoclonal Antibody

Description

EnkiLife offers the B7H3 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: CD276; B7-H3; B7RP-2; 4Ig-B7-H3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.