
T3025 · 1 x 106 cells / 1.0 mL
abm good · Cat: T3025
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abmgood.com/bak-knockout-immortalized-mouse-kidney-epithelia...Description
Key regulators of apoptosis, such as members of the BCL-2 family, have long been linked to the development of cancer. The Bak Knockout Immortalized Mouse Kidney Epithelial Cells bak-/- iBMK is derived from stable transformation of E1A and p53DD into primary baby kidney epithelial cells from C57B/6J mice deficient for Bak. Together with the wild-type iBMK T0082 , Bax knockout iBMK bax-/- iBMK, T3024 and Bak and Bax Double Knockdown iBMK Bak-/-/Bax-/-iBMK, T3026 , these cell lines are suitable in studying the relationships between BCL-2 family and cancer progression, prognosis and significance to treatment.







