Balanol

Description

Balanol Ophiocordin; Azepinostatin is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes ?, ?-I, ?-II, ?, ?, ?, ? IC50s=4-9 nM and ? IC50=150 nM . Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein CREB and myristoylated alanine-rich C kinase substrate MARCKS . Balanol can be isolated from the fungus Verticillium balanoides.