GENERAL CATALOGUE
Balinatunfib
HY-160412 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-160412
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medchemexpress.com/tnf%CE%B1-activity-modulator-3.htmlCatalog No: HY-160412
CAS No: 2248726-53-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Balinatunfib SAR-441566 is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNF? sTNF? trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 without affecting TNFR2 and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases.
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