BAM(8-22) TFA

Description

BAM 8-22 TFA, a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor SNSR agonist, is a potent activator of Mas-related G-protein-coupled receptors Mrgprs , MrgprC11 and hMrgprX1. BAM 8-22 TFA induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM 8-22 TFA has an analgesic effect and can also inhibit the activation of microglia.