GENERAL CATALOGUE
BAY-293
HY-114398 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-114398
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Catalog No: HY-114398
CAS No: 2244904-70-7
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BAY-293, a valuable chemical probe, blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM. BAY-293 is a potent inhibitor of Son of Sevenless 1 SOS1 . SOS1 is the guanine nucleotide exchange factor GEF and activator of RAS.
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