GENERAL CATALOGUE
BC-1901S
HY-160876 · 5 mg
MedChemExpress · Cat: HY-160876
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medchemexpress.com/bc-1901s.htmlCatalog No: HY-160876
CAS No: 1358617-36-3
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
BC-1901S is a proteasome-independent NRF2 activator and stabilizer. BC-1901S binds to DCAF1 E3 ligase subunit and disrupts NRF2/DCAF1 interaction, and activates NRF2 by inhibiting NRF2 ubiquitination in a KEAP1-independent manner. BC-1901S shows anti-inflammatory effect in a murine model of LPS-induced acute lung injury.
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