GENERAL CATALOGUE
BC-LI-0186
HY-136265 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-136265
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/bc-li-0186.htmlCatalog No: HY-136265
CAS No: 695207-56-8
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase LRS; LeuRS and Ras-related GTP-binding protein D RagD interaction IC50=46.11 nM . BC-LI-0186 competitively binds to the RagD interacting site of LRS Kd=42.1 nM and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated?MTOR?mutants and the growth of rapamycin-resistant cancer cells.?BC-LI-0186 is a promising agent for lung cancer research.
More from MedChemExpress
(R)-Trolox (Standard)
HY-101445AR
Metabolic Enzyme Protease
Propentofylline-d6
HY-107203S
Metabolic Enzyme Protease
PTP1B-IN-2
HY-100462
Metabolic Enzyme Protease
Stearic acid-PEG-Mal, MW 2000
HY-W440950
Metabolic Enzyme Protease
Enazadrem phosphate
HY-U00024A
Metabolic Enzyme Protease
1,2-Dihexanoyl-sn-glycero-3-phosphocholine
HY-W127457
Metabolic Enzyme Protease
(R)-KT109
HY-126031
Metabolic Enzyme Protease
?-Glucosidase-IN-31
HY-149409
Metabolic Enzyme Protease