

HY-149418 · 50 mg
MedChemExpress · Cat: HY-149418
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medchemexpress.com/bche-hdac6-in-2.htmlDescription
BChE/HDAC6-IN-2 compound 29a is a dual inhibitor of BChE and HDAC6 with IC50s of 1.8 nM and 71.0 nM, respectively. BChE/HDAC6-IN-2 has prominently neuroprotective effects and reactive oxygen species ROS scavenging activity. BChE/HDAC6-IN-2 is also an effective chelator of metal ion Fe2+ and Cu2+ . BChE/HDAC6-IN-2 inhibits phosphorylation of tau, and exhibits moderate immunomodulatory effect.





