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Bcl-2-IN-11
GENERAL CATALOGUE

Bcl-2-IN-11

HY-153953 · 50 mg

MedChemExpress · Cat: HY-153953

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medchemexpress.com/bcl-2-in-11.html
Catalog No: HY-153953
CAS No: 2760536-88-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Bcl-2-IN-11 compound 6 is a potent and selective Bcl-2 activity inhibitor, with an IC50 of 0.9 nM. Bcl-2-IN-11 shows weak inhibition of Bcl-xl IC50 1000 nM. Bcl-2-IN-11 can be used for the research of a variety of cancers caused by abnormal overexpression of Bcl-2 family proteins: especially malignant hematologic diseases of acute lymphoid leukemia, etc. Bcl-2-IN-11 can also avoid toxic side effects caused by Bcl-xl inhibition, such as thrombocytopenia.

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