

HY-161786 · 50 mg
MedChemExpress · Cat: HY-161786
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Manufacturer product page
medchemexpress.com/bcl-2-in-20.html
Description
Bcl-2-IN-20 Compound 81 is an inhibitor for Bcl-2 with IC50 10 ?M 79.1 % inhibition at 9 ?M . Bcl-2-IN-20 exhibits cytotoxicity in SK-MEL-28 IC50 10 ?M , A549 IC50=6.1 ?M , HepG2 IC50 10 ?M, MCF-7 IC50=8.9 ?M , HCT116 IC50 10 ?M and HEK-293 IC50=14.1 ?M . Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage.







