GENERAL CATALOGUE
Bcl-2-IN-6
HY-144791 · 50 mg
MedChemExpress · Cat: HY-144791
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Manufacturer product page
medchemexpress.com/bcl-2-in-6.htmlCatalog No: HY-144791
CAS No: 3027734-50-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Bcl-2-IN-6 compound 10 is a potent Bcl-2 B-cell lymphoma-2 inhibitor. Bcl-2-IN-7 down-regulates the expression of Bcl-2, and increases the expression of p53, Bax, and caspase-7 mRNA. Bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast cancer MCF-7 cells. Bcl-2-IN-7 shows good anticancer activity, with IC50 values of 20.91, 22.30, 42.29, and 48.00 ?M against MCF-7, LoVo, HepG2, and A549 cell lines, respectively.
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