GENERAL CATALOGUE
BDA-366
HY-101083 · 1 mg
MedChemExpress · Cat: HY-101083
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Catalog No: HY-101083
CAS No: 1909226-00-1
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
BDA-366 is a potent Bcl2 antagonist Ki = 3.3 nM , binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells.
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