GENERAL CATALOGUE
BDM-2
HY-153094 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153094
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Catalog No: HY-153094
CAS No: 1643876-33-8
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BDM-2 is an IN-LEDGF allosteric inhibitor INLAI of HIV-1 integrase IN refers to integrase IC50=47 nM with potent anti-Retroviral ARV activity. BDM-2 shows IN multimerization activation effect with an AC50 value of 20 nM. BDM-2 blocks the interaction between the catalytic core domain of IN IN-CCD and the Integrase binding domain of LEDGF/p75 IBD , with an IC50 value of 0.15 ?M. BDM-2 exhibits highly selective and favorable cytotoxicity.
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