

HY-156237 · 5 mg
MedChemExpress · Cat: HY-156237
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medchemexpress.com/beclin1-atg14l-interaction-inhibitor-1.ht...
Description
Beclin1-ATG14L interaction inhibitor 1 com 19 is a selective Beclin1-ATG14L interaction inhibitor. This protein interaction mechanism specifically targets complex I of the lipid kinase VPS34 without affecting complex II. Because the integrity of VPS34 complex II depends on the Beclin 1-UVRAG interaction. Beclin1-ATG14L interaction inhibitor 1 can disrupt the formation of VPS34 complex I and inhibit autophagy, but does not affect complex II-related vesicle transport.







