GENERAL CATALOGUE
Benzoylaconine
HY-N0217 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0217
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Catalog No: HY-N0217
CAS No: 466-24-0
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Benzoylaconine Benzoylaconitine is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist EC50: 1.5 ?M with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-?B pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects.
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