GENERAL CATALOGUE
Benzoylmesaconine
HY-N0218 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0218
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medchemexpress.com/Benzoylmesaconine.htmlCatalog No: HY-N0218
CAS No: 63238-67-5
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Benzoylmesaconine is a monoester-type alkaloid and is the most abundant component of Wutou decoction, which is widely used in China for rheumatoid arthritis. Benzoylmesaconine exhibits potent anti-inflammatory properties by inhibiting NF-?B. Benzoylmesaconine can suppress NLRP3 inflammasome activation by inhibiting IL-1? secretion and GSDMD-N protein expression. Benzoylmesaconine reduces intracellular K+ efflux and disrupts NLRP3 inflammasome assembly.
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