

HY-14942 · 1 mg
MedChemExpress · Cat: HY-14942
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medchemexpress.com/berubicin.html
Description
Berubicin RTA 744 free base is a Doxorubicin HY-15142A analog that can cross the blood-brain barrier. Berubicin inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme GBM . Berubicin exerts toxic effects on leukemia cells by activating nuclear factor ?B NF-?B and induces apoptosis in neuroblastoma cells. Berubicin can be used in the study of tumors related to the nervous system.







