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Berubicin hydrochloride
GENERAL CATALOGUE

Berubicin hydrochloride

HY-14942A · 1 mg

MedChemExpress · Cat: HY-14942A

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Catalog No: HY-14942A
CAS No: 293736-67-1
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

Berubicin RTA 744 hydrochloride is a Doxorubicin HY-15142A analog that can cross the blood-brain barrier. Berubicin hydrochloride inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme GBM . Berubicin hydrochloride exerts toxic effects on leukemia cells by activating nuclear factor ?B NF-?B and induces apoptosis in neuroblastoma cells. Berubicin hydrochloride can be used in the study of tumors related to the nervous system.

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