GENERAL CATALOGUE
Bfl-1-IN-3
HY-162642 · 50 mg
MedChemExpress · Cat: HY-162642
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Manufacturer product page
medchemexpress.com/bfl-1-in-3.htmlCatalog No: HY-162642
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Bfl-1-IN-3 Compound 56 is a selective, competitive inhibitor for Bfl-1 on BID binding site with Ki of 105 nM. Bfl-1-IN-3 inhibits the proliferation of cell pfeiffer and MV4-11, with IC50 of 6.92 ?M and 12.6 ?M. Bfl-1-IN-3 induces apoptosis in pfeiffer cells. Bfl-1-IN-3 overcomes Venetoclax HY-15531 resistance at the cellular level, and shows synergistically enhanced anti-tumor activity with Venetoclax.
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