GENERAL CATALOGUE
BG11
HY-172092 · 50 mg
MedChemExpress · Cat: HY-172092
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Catalog No: HY-172092
CAS No: 3065877-52-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
BG11 induces the accumulation of Fe2+ and intracellular lipid peroxides, induces ferroptosis. BG11 regulates the expression of Bax and Bcl-2 proteins, and induces apoptosis in MDA-MB-231 cell. BG11 arrests the cell cycle at G0/G1 and S phase, inhibits the proliferation of TNBC cancer cell IC50 for MDA-MB-231 and BT549 is 0.49 ?M and 0.52 ?M , and inhibits the cell migration and invasion. BG11 exhibits antitumor efficacy in mouse models.
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